Safinamide, CAS [[133865-89-1]]

Artikelnummer: FBM-10-2924
Artikelname: Safinamide, CAS [[133865-89-1]]
Artikelnummer: FBM-10-2924
Hersteller Artikelnummer: 10-2924
Alternativnummer: FBM-10-2924-5MG, FBM-10-2924-25MG
Hersteller: Focus Biomolecules
Kategorie: Biochemikalien
Alternative Synonym: Chemical Name: (S)-(+)-2-[[4-(3-Fluorobenzoxy)benzyl]amino]propanamide. Alternate Names: FCE-26743, PNU-151774E, NW-1015
MAO-B inhibitor, Parkinsons therapeutic
Molekulargewicht: 302.34
Reinheit: 98% by HPLC NMr (Conforms)
Formulierung: White solid
CAS Nummer: [133865-89-1]
Formel: C17H19FN2O2
Anwendungsbeschreibung: A selective and reversible inhibitor of monoamine oxidase B (MAO-B, IC50=98 nM with greater than 100-fold selectivity over MAO-A.1 Displays anticonvulsant activity2 and protects against kainate-induced seizures and hippocampal neurodegeneration in rat models3. Reduces overactive glutamatergic signaling via use-dependent sodium channel blockade.4 A novel therapeutic for Parkinsons disease with multiple modes of action.5 Effective as an add-on to dopamine agonist therapy in early Parkinsons.6