Safinamide, CAS [[133865-89-1]]

Product Overview

• Article Name: Safinamide, CAS [[133865-89-1]]
• Biozol Catalog Number: FBM-10-2924
• Supplier Catalog Number: 10-2924
• Alternative Catalog Number: FBM-10-2924-5MG, FBM-10-2924-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: (S)-(+)-2-[[4-(3-Fluorobenzoxy)benzyl]amino]propanamide. Alternate Names: FCE-26743, PNU-151774E, NW-1015

Product Description

MAO-B inhibitor, Parkinsons therapeutic

Product Properties

• Molecular Weight: 302.34
• Purity: 98% by HPLC NMr (Conforms)
• Form: White solid
• CAS Number: [133865-89-1]
• Formula: C17H19FN2O2

Application Notes

• Application Notes: A selective and reversible inhibitor of monoamine oxidase B (MAO-B, IC50=98 nM with greater than 100-fold selectivity over MAO-A.1 Displays anticonvulsant activity2 and protects against kainate-induced seizures and hippocampal neurodegeneration in rat models3. Reduces overactive glutamatergic signaling via use-dependent sodium channel blockade.4 A novel therapeutic for Parkinsons disease with multiple modes of action.5 Effective as an add-on to dopamine agonist therapy in early Parkinsons.6