Chemical Name: Quinolyl-valyl-aspartyl-[2,6-difluorophenoxy]methyl ketone
Caspase inhibitor (pan)
Molekulargewicht:
513.49
Reinheit:
99% by HPLC NMR (Conforms)
Formulierung:
White solid
CAS Nummer:
[1135695-98-5]
Formel:
C26H25F2N3O6
Anwendungsbeschreibung:
Q-VD-OPh is a potent and highly effective pan-caspase inhibitor with potent antiapoptotic activity which is not toxic to cells.1 Displays protective effects on brain damage and bacterial infection in a murine MCAO stroke model.2 Switches doxorubicin-induced apoptosis to an alternative default cell death mode marked by increased expression of senescence markers.3 Blocks staurosporin-induced differentiation of embryonic stem cells to cardiomyocytes.4 Trophoblasts treated with ceramide and Q-VD-OPh undergo necroptosis.5
10-2940
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