Q-VD-OPH, CAS [[1135695-98-5]]

Product Overview

• Article Name: Q-VD-OPH, CAS [[1135695-98-5]]
• Biozol Catalog Number: FBM-10-2940
• Supplier Catalog Number: 10-2940
• Alternative Catalog Number: FBM-10-2940-1MG, FBM-10-2940-5MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: Quinolyl-valyl-aspartyl-[2,6-difluorophenoxy]methyl ketone

Product Description

Caspase inhibitor (pan)

Product Properties

• Molecular Weight: 513.49
• Purity: 99% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [1135695-98-5]
• Formula: C26H25F2N3O6

Application Notes

• Application Notes: Q-VD-OPh is a potent and highly effective pan-caspase inhibitor with potent antiapoptotic activity which is not toxic to cells.1 Displays protective effects on brain damage and bacterial infection in a murine MCAO stroke model.2 Switches doxorubicin-induced apoptosis to an alternative default cell death mode marked by increased expression of senescence markers.3 Blocks staurosporin-induced differentiation of embryonic stem cells to cardiomyocytes.4 Trophoblasts treated with ceramide and Q-VD-OPh undergo necroptosis.5