Leelamine HCl, CAS [[16496-99-4]]

Produktübersicht

• Artikelname: Leelamine HCl, CAS [[16496-99-4]]
• Artikelnummer: FBM-10-2955
• Hersteller Artikelnummer: 10-2955
• Alternativnummer: FBM-10-2955-10MG, FBM-10-2955-50MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: (1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1-,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenemethanamine hydrochloride. Alternate Names: Lylamine HCl, (+)-Dehydroabietylamine HCl

Produktbeschreibung

Intracellular cholesterol inhibitor

Produkteigenschaften

• Molekulargewicht: 321.93
• Reinheit: 98% by TLC NMR (Conforms)
• Formulierung: Off-white or beige solid
• CAS Nummer: [16496-99-4]
• Formel: C20H31N HCl

Anwendungsbeschreibung

• Anwendungsbeschreibung: A lysosomotropic, intracellular cholesterol transport inhibitor with potential chemotherapeutic activity. Induces cholesterol accumulation in lysosomal/endosomal cell compartments via inhibition of autophagic flux.1 Induces apoptosis in breast cancer2, melanoma3 and prostate cancer cells4. A selective inducer of cytochrome P450 2B.5 Inhibits pyruvate dehydrogenase kinase (PDK), IC50=9.5 µM.6

Bilder

10-2955