Embelin, CAS [[550-24-3]]

Produktübersicht

• Artikelname: Embelin, CAS [[550-24-3]]
• Artikelnummer: FBM-10-2959
• Hersteller Artikelnummer: 10-2959
• Alternativnummer: FBM-10-2959-10MG, FBM-10-2959-50MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 2,5-Dihydroxy-3-undecyl-2,5-cyclohexadiene-1,4-dione

Produktbeschreibung

XIAP inhibitor, Apoptosis inducer

Produkteigenschaften

• Molekulargewicht: 294.39
• Reinheit: 98% by HPLC, NMR (Conforms)
• Formulierung: Dark orange solid
• CAS Nummer: [550-24-3]
• Formel: C17H26O4

Anwendungsbeschreibung

• Anwendungsbeschreibung: Inhibits the lysine acetyl transferase PCAF in vitro and in vivo (in vitro IC50=7.2 µM). Inhibits H3K9 acetylation in mouse liver tissue while leaving levels of H3K14, H4K8, H4K12 unchanged1. Also inhibits X-linked inhibitor of apoptosis (XIAP) (IC50 = 4.1 µM, competing with Smac peptide). Binds to the BIR3 domain, preventing XIAP interaction with caspase-9 and Smac. Induces apoptosis and alters gene expression profiles in breast cancer cells3. Possesses anti-inflammatory and analgesic activity in vivo4. Cell-permeable.