PAC-1, CAS [[315183-21-2]]

Produktübersicht

• Artikelname: PAC-1, CAS [[315183-21-2]]
• Artikelnummer: FBM-10-2979
• Hersteller Artikelnummer: 10-2979
• Alternativnummer: FBM-10-2979-5MG,FBM-10-2979-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 4-(Phenylmethyl)-1-piperazineacetic acid [[2-hydroxy-3-(2-propenyl)phenyl]-methylene]hydrazide

Produktbeschreibung

Procaspase activator

Produkteigenschaften

• Molekulargewicht: 392.49
• Reinheit: 98% by HPLC, NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [315183-21-2]
• Formel: C23H28N4O2

Anwendungsbeschreibung

• Anwendungsbeschreibung: PAC-1 is a procaspase-activating compound, directly activating procaspase-3, producing caspase-3, EC50=0.22 µM.1 It is less potent at activating procaspase-7, EC50=4.5 µM. It induces apoptosis in a variety of cancer cell lines. The mechanism of activation involves sequestering inhibitory zinc ions thus allowing procaspase-3 to autoactivate.2 Sensitizes cancer cells to various chemotherapeutic agents.3

Bilder

10-2979