Nilvadipine, CAS [[75530-68-6]]

Produktübersicht

• Artikelname: Nilvadipine, CAS [[75530-68-6]]
• Artikelnummer: FBM-10-3035
• Hersteller Artikelnummer: 10-3035
• Alternativnummer: FBM-10-3035-50MG, FBM-10-3035-250MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 2-Cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-methyl 5-(1-methylethyl) ester. Alternate Names: FR34235

Produktbeschreibung

Syk inhibitor and Ca channel blocker

Produkteigenschaften

• Molekulargewicht: 385.38
• Reinheit: 98% by TLC, NMR (Conforms)
• Formulierung: Yellow solid
• CAS Nummer: [75530-68-6]
• Formel: C19H19N3O6

Anwendungsbeschreibung

• Anwendungsbeschreibung: A novel DHP L-type Ca2+ channel blocker that also inhibits Syk.1 Blocks Abeta production, APPbeta secretion and reduces BACE-1 expression in CHO cells over-expressing Abeta in vitro. Enhances clearance of Abeta across the blood brain barrier in vivo. Reduces brain Abeta levels in a mouse tauopathy model.1 Clinically useful antihypertensive agent.2 Has been shown to prevent cognitive decline in some clinical trials.3 Produces a protective effect on glutamate neurotoxicity in retinal ganglion cells, an effect not shared by other L-type Ca2+ channel blockers such as nifedipine and diltiazem.4