Flavopiridol HCl, CAS [[131740-09-5]]

Produktübersicht

• Artikelname: Flavopiridol HCl, CAS [[131740-09-5]]
• Artikelnummer: FBM-10-3063
• Hersteller Artikelnummer: 10-3063
• Alternativnummer: FBM-10-3063-5MG, FBM-10-3063-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 3-(3-Chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-4H-1-benzopyran-4-one, hydrochloride. Alternate Names: L 86-8275, Alvocidib, NSC-649890

Produktbeschreibung

CDK inhibitor

Produkteigenschaften

• Molekulargewicht: 438.30
• Reinheit: 98% by HPLC, NMR (Conforms)
• Formulierung: Light yellow solid
• CAS Nummer: [131740-09-5]
• Formel: C21H20ClNO5 HCl

Anwendungsbeschreibung

• Anwendungsbeschreibung: Cyclin-dependent kinase (CDK) inhibitor that causes cell cycle arrest at G1 and G2 phase1. Potentiates (100-200 nM) PMA-induced apoptosis in HL-60 and U937 cells2. Potentiates the effects of topoisomerase I inhibitors by suppressing Rad51 expression in a p53-dependent manner. Displays potent antiviral activity against HIV-1 and HSV-1 in vitro4.