Flavopiridol HCl, CAS [[131740-09-5]]

Product Overview

• Article Name: Flavopiridol HCl, CAS [[131740-09-5]]
• Biozol Catalog Number: FBM-10-3063
• Supplier Catalog Number: 10-3063
• Alternative Catalog Number: FBM-10-3063-5MG, FBM-10-3063-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 3-(3-Chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-4H-1-benzopyran-4-one, hydrochloride. Alternate Names: L 86-8275, Alvocidib, NSC-649890

Product Description

CDK inhibitor

Product Properties

• Molecular Weight: 438.30
• Purity: 98% by HPLC, NMR (Conforms)
• Form: Light yellow solid
• CAS Number: [131740-09-5]
• Formula: C21H20ClNO5 HCl

Application Notes

• Application Notes: Cyclin-dependent kinase (CDK) inhibitor that causes cell cycle arrest at G1 and G2 phase1. Potentiates (100-200 nM) PMA-induced apoptosis in HL-60 and U937 cells2. Potentiates the effects of topoisomerase I inhibitors by suppressing Rad51 expression in a p53-dependent manner. Displays potent antiviral activity against HIV-1 and HSV-1 in vitro4.