NSC59984, CAS [[803647-40-7]]

Produktübersicht

• Artikelname: NSC59984, CAS [[803647-40-7]]
• Artikelnummer: FBM-10-3148
• Hersteller Artikelnummer: 10-3148
• Alternativnummer: FBM-10-3148-5MG, FBM-10-3148-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: (E)-1-(4-Methylpiperazin-1-yl)-3-(5-nitrofuran-2-yl)prop-2-en-1-one

Produktbeschreibung

p53 activator

Produkteigenschaften

• Molekulargewicht: 265.27
• Reinheit: 98% by TLC NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [803647-40-7]
• Formel: C12H15N3O4

Anwendungsbeschreibung

• Anwendungsbeschreibung: p53 activator. Restores wild-type p53 signaling and depletes mutant p53 gain of function. Induces mutant p53 protein degradation via MDM2 and ubiquitin-proteasome pathway. Induces p73-dependent cell death in cancer cells without toxicity toward normal cells.1 Inhibition of p53-MDM2 interaction remains a viable strategy for cancer therapeutic development.2,3