Leu-Leu-OMe HBr, CAS [[16689-14-8]]

Produktübersicht

• Artikelname: Leu-Leu-OMe HBr, CAS [[16689-14-8]]
• Artikelnummer: FBM-10-3220
• Hersteller Artikelnummer: 10-3220
• Alternativnummer: FBM-10-3220-20MG, FBM-10-3220-100MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: Leucyl-leucine methyl ester hydrobromide. Alternate Names: LLME

Produktbeschreibung

Lysosomal damaging agent

Produkteigenschaften

• Molekulargewicht: 339.27
• Reinheit: 98% by HPLC NMr (Conforms)
• Formulierung: White solid
• CAS Nummer: [16689-14-8]
• Formel: C13H26N2O3 HBr

Anwendungsbeschreibung

• Anwendungsbeschreibung: Leu-Leu-OMe is a lysosomal damaging agent (lysosomotropic). It is condensed into a membranolytic polymer via the transpeptidase action of cathepsin C within lysosomes.1,2 May be used to induce a lysosomal damage model in cells.3,4 LLOMe-induced lysosomal damage elicits ubiquitin puncta formation on lysosomes1. Induces apoptosis in human mast cells via lysosome destabilization leaving fibroblasts and HEK-293 cells largely resistant5. Induces lysophagy.4