Leu-Leu-OMe HBr, CAS [[16689-14-8]]

Product Overview

• Article Name: Leu-Leu-OMe HBr, CAS [[16689-14-8]]
• Biozol Catalog Number: FBM-10-3220
• Supplier Catalog Number: 10-3220
• Alternative Catalog Number: FBM-10-3220-20MG, FBM-10-3220-100MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: Leucyl-leucine methyl ester hydrobromide. Alternate Names: LLME

Product Description

Lysosomal damaging agent

Product Properties

• Molecular Weight: 339.27
• Purity: 98% by HPLC NMr (Conforms)
• Form: White solid
• CAS Number: [16689-14-8]
• Formula: C13H26N2O3 HBr

Application Notes

• Application Notes: Leu-Leu-OMe is a lysosomal damaging agent (lysosomotropic). It is condensed into a membranolytic polymer via the transpeptidase action of cathepsin C within lysosomes.1,2 May be used to induce a lysosomal damage model in cells.3,4 LLOMe-induced lysosomal damage elicits ubiquitin puncta formation on lysosomes1. Induces apoptosis in human mast cells via lysosome destabilization leaving fibroblasts and HEK-293 cells largely resistant5. Induces lysophagy.4