C-DIM 12, CAS [[178946-89-9]]

Produktübersicht

• Artikelname: C-DIM 12, CAS [[178946-89-9]]
• Artikelnummer: FBM-10-3280
• Hersteller Artikelnummer: 10-3280
• Alternativnummer: FBM-10-3280-5MG, FBM-10-3280-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 3,3-[(4-Chlorophenyl)methylene]bis[1H-indole]

Produktbeschreibung

Nurr1 activator, NFkappaB inhibitor

Produkteigenschaften

• Molekulargewicht: 356.85
• Reinheit: 98% by TLC, NMR (Conforms)
• Formulierung: Orange solid
• CAS Nummer: [178946-89-9]
• Formel: C23H17ClN2

Anwendungsbeschreibung

• Anwendungsbeschreibung: Activates the orphan nuclear receptor Nurr1 and inhibits bladder cancer growth.1,2 Nurr1 is a suppressor of NFkB-related neuroinflammatory genes in microglia and astrocytes and C-DIM 12 suppresses inflammatory signaling in these cells.3 Displays neuroprotective activity in a mouse model of progressive neurodegeneration with a strong neuroinflammatory component (50 mg/Kg, oral).4