C-DIM 12, CAS [[178946-89-9]]

Product Overview

• Article Name: C-DIM 12, CAS [[178946-89-9]]
• Biozol Catalog Number: FBM-10-3280
• Supplier Catalog Number: 10-3280
• Alternative Catalog Number: FBM-10-3280-5MG, FBM-10-3280-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 3,3-[(4-Chlorophenyl)methylene]bis[1H-indole]

Product Description

Nurr1 activator, NFkappaB inhibitor

Product Properties

• Molecular Weight: 356.85
• Purity: 98% by TLC, NMR (Conforms)
• Form: Orange solid
• CAS Number: [178946-89-9]
• Formula: C23H17ClN2

Application Notes

• Application Notes: Activates the orphan nuclear receptor Nurr1 and inhibits bladder cancer growth.1,2 Nurr1 is a suppressor of NFkB-related neuroinflammatory genes in microglia and astrocytes and C-DIM 12 suppresses inflammatory signaling in these cells.3 Displays neuroprotective activity in a mouse model of progressive neurodegeneration with a strong neuroinflammatory component (50 mg/Kg, oral).4