CK-666, CAS [[442633-00-3]]

Produktübersicht

• Artikelname: CK-666, CAS [[442633-00-3]]
• Artikelnummer: FBM-10-3346
• Hersteller Artikelnummer: 10-3346
• Alternativnummer: FBM-10-3346-5MG, FBM-10-3346-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 2-Fluoro-N-[2-methyl-1H-indol-3-yl)ethyl]benzamide

Produktbeschreibung

ARP2/3 inhibitor

Produkteigenschaften

• Molekulargewicht: 296.34
• Reinheit: 98% by TLC, NMR (Conforms)
• Formulierung: Cream-colored solid
• CAS Nummer: [442633-00-3]
• Formel: C18H17FN2O

Anwendungsbeschreibung

• Anwendungsbeschreibung: A potent, selective and reversible inhibitor of ARP2/3 complex (actin related proteins 2 and 3) with an IC50 = 4 µM for human ARP2/3.1 Blocks actin nucleation and radically alters lamellipodial actin architecture, suspended cell shape and the cell spreading process.2 CK-666 attenuates BBB dysfunction induced by methamphetamine3. It is an important new tool for studying actin assembly and the diverse range of actin-related processes in normal4 and pathophysiology5.

Bilder

10-3346