CK-666, CAS [[442633-00-3]]

Product Overview

• Article Name: CK-666, CAS [[442633-00-3]]
• Biozol Catalog Number: FBM-10-3346
• Supplier Catalog Number: 10-3346
• Alternative Catalog Number: FBM-10-3346-5MG,FBM-10-3346-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 2-Fluoro-N-[2-methyl-1H-indol-3-yl)ethyl]benzamide

Product Description

ARP2/3 inhibitor

Product Properties

• Molecular Weight: 296.34
• Purity: 98% by TLC, NMR (Conforms)
• Form: Cream-colored solid
• CAS Number: [442633-00-3]
• Formula: C18H17FN2O

Application Notes

• Application Notes: A potent, selective and reversible inhibitor of ARP2/3 complex (actin related proteins 2 and 3) with an IC50 = 4 µM for human ARP2/3.1 Blocks actin nucleation and radically alters lamellipodial actin architecture, suspended cell shape and the cell spreading process.2 CK-666 attenuates BBB dysfunction induced by methamphetamine3. It is an important new tool for studying actin assembly and the diverse range of actin-related processes in normal4 and pathophysiology5.

Images

10-3346