AC1903, CAS [[831234-13-0]]

Produktübersicht

• Artikelname: AC1903, CAS [[831234-13-0]]
• Artikelnummer: FBM-10-3375
• Hersteller Artikelnummer: 10-3375
• Alternativnummer: FBM-10-3375-10MG, FBM-10-3375-50MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 1-Benzyl-1H-benzoimidazol-2-yl)-furan-2-ylmethyl-amine

Produktbeschreibung

TRPC5 blocker

Produkteigenschaften

• Molekulargewicht: 303.36
• Reinheit: 98% by TLC NMR (Conforms)
• Formulierung: Beige solid
• CAS Nummer: [831234-13-0]
• Formel: C19H17N3O

Anwendungsbeschreibung

• Anwendungsbeschreibung: A potent and selective TRPC5 blocker. Suppresses severe proteinuria and prevents podocyte loss in a transgenic rat model of focal segmental glomerulosclerosis. It also provided therapeutic benefit in a rat model of hypertensive proteineuric kidney disease. The use of this selective tool compound provided a mechanistic rationale for targeting TRPC5 channels in progressive chronic kidney diseases and paves the way for the discovery of new therapeutics. Active in vivo.