AC1903, CAS [[831234-13-0]]

Product Overview

• Article Name: AC1903, CAS [[831234-13-0]]
• Biozol Catalog Number: FBM-10-3375
• Supplier Catalog Number: 10-3375
• Alternative Catalog Number: FBM-10-3375-10MG, FBM-10-3375-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 1-Benzyl-1H-benzoimidazol-2-yl)-furan-2-ylmethyl-amine

Product Description

TRPC5 blocker

Product Properties

• Molecular Weight: 303.36
• Purity: 98% by TLC NMR (Conforms)
• Form: Beige solid
• CAS Number: [831234-13-0]
• Formula: C19H17N3O

Application Notes

• Application Notes: A potent and selective TRPC5 blocker. Suppresses severe proteinuria and prevents podocyte loss in a transgenic rat model of focal segmental glomerulosclerosis. It also provided therapeutic benefit in a rat model of hypertensive proteineuric kidney disease. The use of this selective tool compound provided a mechanistic rationale for targeting TRPC5 channels in progressive chronic kidney diseases and paves the way for the discovery of new therapeutics. Active in vivo.