PCI-34051, CAS [[950762-95-5]]

Produktübersicht

• Artikelname: PCI-34051, CAS [[950762-95-5]]
• Artikelnummer: FBM-10-3396
• Hersteller Artikelnummer: 10-3396
• Alternativnummer: FBM-10-3396-5MG, FBM-10-3396-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: N-Hydroxy-1-[(4-methoxyphenyl)methyl]-1H-indole-6-carboxamide

Produktbeschreibung

HDAC8 inhibitor

Produkteigenschaften

• Molekulargewicht: 296.33
• Reinheit: >98% by TLC NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [950762-95-5]
• Formel: C17H16N2O3

Anwendungsbeschreibung

• Anwendungsbeschreibung: PCI-34051 is a potent and selective HDAC8 inhibitor (IC50=10 nM) with greater than 200-fold selectivity over HDACs 1, 2, 3, 6, 10.1 Unlike broad-spectrum HDAC inhibitors, it does not cause detectable histone or tubulin acetylation.1 Studies employing PCI-34051 showed that HDAC8 catalyzes the hydrolysis of long chain fatty acyl lysine.2 It is a very useful tool for exploring the role of HDAC8 in cellular function.3-6