PCI-34051, CAS [[950762-95-5]]

Product Overview

• Article Name: PCI-34051, CAS [[950762-95-5]]
• Biozol Catalog Number: FBM-10-3396
• Supplier Catalog Number: 10-3396
• Alternative Catalog Number: FBM-10-3396-5MG, FBM-10-3396-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: N-Hydroxy-1-[(4-methoxyphenyl)methyl]-1H-indole-6-carboxamide

Product Description

HDAC8 inhibitor

Product Properties

• Molecular Weight: 296.33
• Purity: >98% by TLC NMR (Conforms)
• Form: Off-white solid
• CAS Number: [950762-95-5]
• Formula: C17H16N2O3

Application Notes

• Application Notes: PCI-34051 is a potent and selective HDAC8 inhibitor (IC50=10 nM) with greater than 200-fold selectivity over HDACs 1, 2, 3, 6, 10.1 Unlike broad-spectrum HDAC inhibitors, it does not cause detectable histone or tubulin acetylation.1 Studies employing PCI-34051 showed that HDAC8 catalyzes the hydrolysis of long chain fatty acyl lysine.2 It is a very useful tool for exploring the role of HDAC8 in cellular function.3-6