Chemical Name: 2-[1-[4-[2-(4-Chlorophenyoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-quinazolinone
Ferroptosis inducer
Molekulargewicht:
547.04
Reinheit:
98% by HPLC, NMR (Conforms)
Formulierung:
White solid
CAS Nummer:
[571203-78-6]
Formel:
C30H31ClN4O4
Anwendungsbeschreibung:
Ferroptosis inducer.1 Inhibits the cystine-glutamate antiporter, system Xc- leading to activation of an ER stress response.2 Inhibition of system Xc- leads to cysteine starvation, glutathione depletion and induction of ferroptosis.3 Also blocks mitochondrial voltage-dependent anion channels (specifically VDAC2 and 3).4
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