Chemical Name: 2-[1-[4-[2-(4-Chlorophenyoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-quinazolinone
Ferroptosis inducer
Molecular Weight:
547.04
Purity:
98% by HPLC, NMR (Conforms)
Form:
White solid
CAS Number:
[571203-78-6]
Formula:
C30H31ClN4O4
Application Notes:
Ferroptosis inducer.1 Inhibits the cystine-glutamate antiporter, system Xc- leading to activation of an ER stress response.2 Inhibition of system Xc- leads to cysteine starvation, glutathione depletion and induction of ferroptosis.3 Also blocks mitochondrial voltage-dependent anion channels (specifically VDAC2 and 3).4
* VAT and and shipping costs not included. Errors and price changes excepted