RSL3, CAS [[1219810-16-8]]

Produktübersicht

• Artikelname: RSL3, CAS [[1219810-16-8]]
• Artikelnummer: FBM-10-3417
• Hersteller Artikelnummer: 10-3417
• Alternativnummer: FBM-10-3417-5MG, FBM-10-3417-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: (1S,3R)-Methyl 2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-[4-(methoxycarbonyl)phenyl]-1H-pyrido[3,4-b]indole-3-carboxylate. Alternate Names: 1S,3R-RSL3

Produktbeschreibung

GPX4 inhibitor / Ferroptosis inducer

Produkteigenschaften

• Molekulargewicht: 440.88
• Reinheit: >98% by HPLC, NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [1219810-16-8]
• Formel: C23H21ClN2O5

Anwendungsbeschreibung

• Anwendungsbeschreibung: RSL3 inhibits glutathione peroxidase (GPX4) inducing ferroptosis.1,2 Effectively induces ferroptosis in glioblastoma cells.3 Everolimus in combination with RSL3 synergistically inhibits the viability of renal cell carcinoma (RCC) cells suggesting a mechanism by which RCC drug resistance may be overcome.4