RSL3, CAS [[1219810-16-8]]

Product Overview

• Article Name: RSL3, CAS [[1219810-16-8]]
• Biozol Catalog Number: FBM-10-3417
• Supplier Catalog Number: 10-3417
• Alternative Catalog Number: FBM-10-3417-5MG, FBM-10-3417-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: (1S,3R)-Methyl 2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-[4-(methoxycarbonyl)phenyl]-1H-pyrido[3,4-b]indole-3-carboxylate. Alternate Names: 1S,3R-RSL3

Product Description

GPX4 inhibitor / Ferroptosis inducer

Product Properties

• Molecular Weight: 440.88
• Purity: >98% by HPLC, NMR (Conforms)
• Form: Off-white solid
• CAS Number: [1219810-16-8]
• Formula: C23H21ClN2O5

Application Notes

• Application Notes: RSL3 inhibits glutathione peroxidase (GPX4) inducing ferroptosis.1,2 Effectively induces ferroptosis in glioblastoma cells.3 Everolimus in combination with RSL3 synergistically inhibits the viability of renal cell carcinoma (RCC) cells suggesting a mechanism by which RCC drug resistance may be overcome.4