alpha-Mangostin, CAS [[6147-11-1]]

Produktübersicht

• Artikelname: alpha-Mangostin, CAS [[6147-11-1]]
• Artikelnummer: FBM-10-3433
• Hersteller Artikelnummer: 10-3433
• Alternativnummer: FBM-10-3433-10MG, FBM-10-3433-50MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 1,3,6-Trihydroxy-7-methoxy-2,8-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one. Alternate Names: Mangostine, Mangostin

Produktbeschreibung

STING agonist (human)

Produkteigenschaften

• Molekulargewicht: 410.46
• Reinheit: 98% by HPLC NMR (Conforms)
• Formulierung: Yellow solid
• CAS Nummer: [6147-11-1]
• Formel: C24H26O6

Anwendungsbeschreibung

• Anwendungsbeschreibung: alpha-Mangostin is a xanthone natural product that has historically been used in traditional folk medicine.1 It is a potent agonist of human STING (Stimulator of Interferon Genes) and also weakly activates mouse STING.2 Induces IFN- production and repolarizes human monocyte-derived M2 macrophages to M1. Improves insulin secretion and protects INS-1 cells from streptozotocin-induced damage.3 Suppresses the metastasis of human renal carcinoma cells.4 Synergizes with kinase inhibitors in suppression of proliferation of SK-MEL-2 malignant melanoma cells.5