alpha-Mangostin, CAS [[6147-11-1]]

Product Overview

• Article Name: alpha-Mangostin, CAS [[6147-11-1]]
• Biozol Catalog Number: FBM-10-3433
• Supplier Catalog Number: 10-3433
• Alternative Catalog Number: FBM-10-3433-10MG,FBM-10-3433-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Mangostine, Mangostin

Product Description

STING agonist (human)

Product Properties

• Molecular Weight: 410.46
• Purity: 98% by HPLC NMR (Conforms)
• Form: Yellow solid
• CAS Number: [6147-11-1]
• Formula: C24H26O6

Application Notes

• Application Notes: alpha-Mangostin is a xanthone natural product that has historically been used in traditional folk medicine.1 It is a potent agonist of human STING (Stimulator of Interferon Genes) and also weakly activates mouse STING.2 Induces IFN- production and repolarizes human monocyte-derived M2 macrophages to M1. Improves insulin secretion and protects INS-1 cells from streptozotocin-induced damage.3 Suppresses the metastasis of human renal carcinoma cells.4 Synergizes with kinase inhibitors in suppression of proliferation of SK-MEL-2 malignant melanoma cells.5