Napabucasin, CAS [[83280-65-3]]

Produktübersicht

• Artikelname: Napabucasin, CAS [[83280-65-3]]
• Artikelnummer: FBM-10-3442
• Hersteller Artikelnummer: 10-3442
• Alternativnummer: FBM-10-3442-5MG,FBM-10-3442-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 2-Acetylnsphtho[2,3-b]furan-4,9-dione. Alternate Names: BBI608

Produktbeschreibung

STAT3 inhibitor / Cancer cell stemness inhibitor

Produkteigenschaften

• Molekulargewicht: 240.21
• Reinheit: 98% by TLC NMR (Conforms)
• Formulierung: Yellow solid
• CAS Nummer: [83280-65-3]
• Formel: C14H8O4

Anwendungsbeschreibung

• Anwendungsbeschreibung: Inhibits gene transcription driven by STAT3. Inhibits cancer cell stemness gene expression and blocks spherogenesis of stemness-high cancer cells isolated from a variety of cancer types.1 Effective antitumor agent as a monotherapy or in combination with other agents such as taxol in mouse models.2 Clinical trials have demonstrated encouraging anti-tumor activity with the potential to suppress metastasis and prevent relapse in patients with various types of cancer.2,3 Overcomes cisplatin resistance in non-small cell lung cancer.4

Bilder

10-3442