Napabucasin, CAS [[83280-65-3]]

Product Overview

• Article Name: Napabucasin, CAS [[83280-65-3]]
• Biozol Catalog Number: FBM-10-3442
• Supplier Catalog Number: 10-3442
• Alternative Catalog Number: FBM-10-3442-5MG, FBM-10-3442-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 2-Acetylnsphtho[2,3-b]furan-4,9-dione. Alternate Names: BBI608

Product Description

STAT3 inhibitor / Cancer cell stemness inhibitor

Product Properties

• Molecular Weight: 240.21
• Purity: 98% by TLC NMR (Conforms)
• Form: Yellow solid
• CAS Number: [83280-65-3]
• Formula: C14H8O4

Application Notes

• Application Notes: Inhibits gene transcription driven by STAT3. Inhibits cancer cell stemness gene expression and blocks spherogenesis of stemness-high cancer cells isolated from a variety of cancer types.1 Effective antitumor agent as a monotherapy or in combination with other agents such as taxol in mouse models.2 Clinical trials have demonstrated encouraging anti-tumor activity with the potential to suppress metastasis and prevent relapse in patients with various types of cancer.2,3 Overcomes cisplatin resistance in non-small cell lung cancer.4