TPPU, CAS [[1222780-33-7]]

Produktübersicht

• Artikelname: TPPU, CAS [[1222780-33-7]]
• Artikelnummer: FBM-10-3451
• Hersteller Artikelnummer: 10-3451
• Alternativnummer: FBM-10-3451-5MG,FBM-10-3451-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien

Produktbeschreibung

Soluble epoxide hydrolase inhibitor

Produkteigenschaften

• Molekulargewicht: 359.35
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: White or off-white solid
• CAS Nummer: [1222780-33-7]
• Formel: C16H20F3N3O3

Anwendungsbeschreibung

• Anwendungsbeschreibung: TPPU is a potent and selective inhibitor of both murine and human soluble epoxide hydrolase, IC50=2.8 and 3.7 nM respectively.1 It alleviated blood brain barrier damage and attenuated neuronal injury in a mouse intracerebral hemorrhage model2 and displays neuroprotective effects in ischemic injury3. It reduces neuroinflammation in a mouse model of Alzheimers disease.4 It improves insulin resistance and reduced hypertension in mouse models.5 Cell permeable and active in vivo.