Autophinib, CAS [[1644443-47-9]]

Produktübersicht

• Artikelname: Autophinib, CAS [[1644443-47-9]]
• Artikelnummer: FBM-10-3476
• Hersteller Artikelnummer: 10-3476
• Alternativnummer: FBM-10-3476-5MG, FBM-10-3476-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 6-Chloro-N-(5-methyl-1H-pyrazol-3-yl)-2-(4-nitrophenoxy)-4-pyrimidinamine

Produktbeschreibung

Autophagy inhibitor

Produkteigenschaften

• Molekulargewicht: 346.73
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [1644443-47-9]
• Formel: C14H11ClN6O3

Anwendungsbeschreibung

• Anwendungsbeschreibung: Inhibits autophagy induced by starvation or rapamycin by inhibiting the lipid kinase VPS34 (IC50=19 nM).1 Increased autophagy and apoptosis were rescued by autophinib in Per1-overexpressing oral squamous cell carcinoma cells.2 Autophinib has quickly become an important biochemical tool for inhibition of autophagy in a variety of cellular contexts.3-5