4-Octyl itaconate, CAS [[3133-16-2]]

Produktübersicht

• Artikelname: 4-Octyl itaconate, CAS [[3133-16-2]]
• Artikelnummer: FBM-10-3573
• Hersteller Artikelnummer: 10-3573
• Alternativnummer: FBM-10-3573-20MG,FBM-10-3573-100MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien

Produktbeschreibung

Nrf2 activator

Produkteigenschaften

• Molekulargewicht: 242.32
• Reinheit: >98% by TLC NMR (Conforms)
• Formulierung: White to off-white solid
• CAS Nummer: [3133-16-2]
• Formel: C13H22O4

Anwendungsbeschreibung

• Anwendungsbeschreibung: 4-Octyl itaconate is a cell-permeable analog of itaconic acid which activates the anti-inflammatory transcription factor Nrf2 via alkylation of KEAP1.1 It inhibits various forms of cell death including ferroptosis2 and gasdermin B-mediated pyroptosis3 while inducing secretion of anti-inflammatory proteins4 and promoting a wound-resolving phenotype in pro-inflammatory macrophages5.