4-Octyl itaconate, CAS [[3133-16-2]]

Product Overview

• Article Name: 4-Octyl itaconate, CAS [[3133-16-2]]
• Biozol Catalog Number: FBM-10-3573
• Supplier Catalog Number: 10-3573
• Alternative Catalog Number: FBM-10-3573-20MG, FBM-10-3573-100MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 4-Octyl methylenesuccinate, n-Octyl 3-carboxy-3-butenoate

Product Description

Nrf2 activator

Product Properties

• Molecular Weight: 242.32
• Purity: >98% by TLC NMR (Conforms)
• Form: White to off-white solid
• CAS Number: [3133-16-2]
• Formula: C13H22O4

Application Notes

• Application Notes: 4-Octyl itaconate is a cell-permeable analog of itaconic acid which activates the anti-inflammatory transcription factor Nrf2 via alkylation of KEAP1.1 It inhibits various forms of cell death including ferroptosis2 and gasdermin B-mediated pyroptosis3 while inducing secretion of anti-inflammatory proteins4 and promoting a wound-resolving phenotype in pro-inflammatory macrophages5.