Santacruzamate A, CAS [[1477949-42-0]]

Produktübersicht

• Artikelname: Santacruzamate A, CAS [[1477949-42-0]]
• Artikelnummer: FBM-10-3613
• Hersteller Artikelnummer: 10-3613
• Alternativnummer: FBM-10-3613-5MG,FBM-10-3613-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien

Produktbeschreibung

HDAC2 inhibitor

Produkteigenschaften

• Molekulargewicht: 278.35
• Reinheit: 98% by TLC NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [1477949-42-0]
• Formel: C15H22N2O3

Anwendungsbeschreibung

• Anwendungsbeschreibung: A highly potent and selective inhibitor of HDAC2 isolated from the Panamanian marine cyanobacterium cf. Symploca (IC50=0.119 and 434 nM for HDAC2 and HDAC6 respectively).1 Induces apoptosis and cancer cell death only in combination with other HDAC1 inhibitors.2 Potential therapeutic agent for breast cancer.3 Attenuates A fragment (A25-35)-induced toxicity in PC12 cells by enhancing ER stress tolerance.4 Ameliorates Alzheimers disease-like pathology in mouse models.4