Ozanimod, CAS [[1306760-87-1]]

Artikelnummer: FBM-10-3739
Artikelname: Ozanimod, CAS [[1306760-87-1]]
Artikelnummer: FBM-10-3739
Hersteller Artikelnummer: 10-3739
Alternativnummer: FBM-10-3739-5MG, FBM-10-3739-25MG
Hersteller: Focus Biomolecules
Kategorie: Biochemikalien
Alternative Synonym: Chemical Name: 5-[3-[(1S)-2,3-Dihydro-1-[(2-hydroxyethyl)amino]-1H-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-(1-methylethoxy)-benzonitrile. Alternate Names: RPC1063
Sphingosine-1-phosphate receptor agonist
Molekulargewicht: 404.47
Reinheit: >98% by HPLC, NMR (Conforms)
Formulierung: White solid
CAS Nummer: [1306760-87-1]
Formel: C23H24N4O3
Anwendungsbeschreibung: Ozanimod binds to human recombinant sphingosine-1-phosphate receptor S1P1 and S1P5 receptors in a competitive radioligand binding assay. Agonism at S1P1 receptors induced receptor internalization whereas S1P5 did not.1 It displays anti-inflammatory activity and is in clinical use for multiple sclerosis2 and inflammatory bowel disease3. It reduces chronic inflammation and alleviates kidney pathology in systemic lupus erythematosus in a mouse model.4