Ozanimod, CAS [[1306760-87-1]]

Product Overview

• Article Name: Ozanimod, CAS [[1306760-87-1]]
• Biozol Catalog Number: FBM-10-3739
• Supplier Catalog Number: 10-3739
• Alternative Catalog Number: FBM-10-3739-5MG, FBM-10-3739-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 5-[3-[(1S)-2,3-Dihydro-1-[(2-hydroxyethyl)amino]-1H-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-(1-methylethoxy)-benzonitrile. Alternate Names: RPC1063

Product Description

Sphingosine-1-phosphate receptor agonist

Product Properties

• Molecular Weight: 404.47
• Purity: >98% by HPLC, NMR (Conforms)
• Form: White solid
• CAS Number: [1306760-87-1]
• Formula: C23H24N4O3

Application Notes

• Application Notes: Ozanimod binds to human recombinant sphingosine-1-phosphate receptor S1P1 and S1P5 receptors in a competitive radioligand binding assay. Agonism at S1P1 receptors induced receptor internalization whereas S1P5 did not.1 It displays anti-inflammatory activity and is in clinical use for multiple sclerosis2 and inflammatory bowel disease3. It reduces chronic inflammation and alleviates kidney pathology in systemic lupus erythematosus in a mouse model.4