TG-100572 HCl, CAS [[867331-64-4]]

Produktübersicht

• Artikelname: TG-100572 HCl, CAS [[867331-64-4]]
• Artikelnummer: FBM-10-3778
• Hersteller Artikelnummer: 10-3778
• Alternativnummer: FBM-10-3778-1MG, FBM-10-3778-5MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 4-Chloro-3-(5-methyl-3-((4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)amino)benzo[e][1,2,4]triazin-7-yl)phenol hydrochloride

Produktbeschreibung

Multi-kinase inhibitor

Produkteigenschaften

• Molekulargewicht: 512.44
• Reinheit: >98% by HPLC NMR (conforms)
• Formulierung: Pink solid
• CAS Nummer: [867331-64-4]
• Formel: C26H26ClN5O2 HCl

Anwendungsbeschreibung

• Anwendungsbeschreibung: TG-100572 is a multi-targeted kinase inhibitor that inhibits selected receptor kinases and Src kinases. IC50s = 2, 7, 2, 16, 13 VEGFR1, VEGFR2, FGFR1, FGFR2 PDGFRbeta and 5, 0.5, 6, 0.1, 0.4, 1, 0.2 nM for Fgr, Fyn, Hck, Lck, Lyn, Src and Yes respectively.1 It suppresses choroidal neovascularization and retinal edema1. Blocks angiogenesis caused by HSV infection in the mouse eye.2 A prodrug strategy has been employed for topically applied AMD treatment.3