UPF-1069, CAS [[1048371-03-4]]

Produktübersicht

• Artikelname: UPF-1069, CAS [[1048371-03-4]]
• Artikelnummer: FBM-10-3779
• Hersteller Artikelnummer: 10-3779
• Alternativnummer: FBM-10-3779-5MG, FBM-10-3779-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 5-(2-Oxo-3-phenylethoxy)-1(2H)-isoquinolinone

Produktbeschreibung

PARP-2 inhibitor

Produkteigenschaften

• Molekulargewicht: 279.29
• Reinheit: 98% by TLC, NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [1048371-03-4]
• Formel: C17H13NO3

Anwendungsbeschreibung

• Anwendungsbeschreibung: A selective PARP-2 inhibitor (IC50=0.3 µM and ~ 27-fold selective against PARP-1).1,2 Increases apoptosis in hippocampal slices but protects cortical cells in models of post-ischemic brain damage.3 Blocks the interaction between PARP-2 and FOXA1, attenuating androgen receptor-mediated gene expression and inhibiting androgen receptor-positive prostate cancer growth.4