UPF-1069, CAS [[1048371-03-4]]

Product Overview

• Article Name: UPF-1069, CAS [[1048371-03-4]]
• Biozol Catalog Number: FBM-10-3779
• Supplier Catalog Number: 10-3779
• Alternative Catalog Number: FBM-10-3779-5MG, FBM-10-3779-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 5-(2-Oxo-3-phenylethoxy)-1(2H)-isoquinolinone

Product Description

PARP-2 inhibitor

Product Properties

• Molecular Weight: 279.29
• Purity: 98% by TLC, NMR (Conforms)
• Form: Off-white solid
• CAS Number: [1048371-03-4]
• Formula: C17H13NO3

Application Notes

• Application Notes: A selective PARP-2 inhibitor (IC50=0.3 µM and ~ 27-fold selective against PARP-1).1,2 Increases apoptosis in hippocampal slices but protects cortical cells in models of post-ischemic brain damage.3 Blocks the interaction between PARP-2 and FOXA1, attenuating androgen receptor-mediated gene expression and inhibiting androgen receptor-positive prostate cancer growth.4