Elafibranor, CAS [[923978-27-2]]

Produktübersicht

• Artikelname: Elafibranor, CAS [[923978-27-2]]
• Artikelnummer: FBM-10-3901
• Hersteller Artikelnummer: 10-3901
• Alternativnummer: FBM-10-3901-5MG, FBM-10-3901-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 2-[2,6-Dimethyl-4-[(E)-3-(4-methylsulfanylphenyl)-3-oxoprop-1-enyl]phenoxy]-2-methylpropanoic acid. Alternate Names: GFT505

Produktbeschreibung

PPARalpha/delta agonist

Produkteigenschaften

• Molekulargewicht: 384.49
• Reinheit: 98% by HPLC NMr (Conforms)
• Formulierung: Pale yellow solid
• CAS Nummer: [923978-27-2]
• Formel: C22H24O4S

Anwendungsbeschreibung

• Anwendungsbeschreibung: Elafibranor is a dual PPARalpha/delta agonist (EC50 PPARalpha = 10-20 nM, PPARdelta = 100-150 nM).1 It was able to decrease plasma triglycerides levels1, increase HDL cholesterol levels in human studies1, and improve hepatic and peripheral insulin sensitivity2. Elafibranors antidiabetic effects in db/db were without the adverse cardiac effects seen in PPARgamma agonism.3 Elafibranor has also been shown to have therapeutic promise in the treatment of nonalcoholic steatohepatitis (NASH).4-6