KL101, CAS [[396721-89-4]]

Artikelnummer: FBM-10-3907
Artikelname: KL101, CAS [[396721-89-4]]
Artikelnummer: FBM-10-3907
Hersteller Artikelnummer: 10-3907
Alternativnummer: FBM-10-3907-5MG, FBM-10-3907-25MG
Hersteller: Focus Biomolecules
Kategorie: Biochemikalien
Alternative Synonym: Chemical Name: N-(2-(2,4-Dimethylphenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-yl)-3,4-dimethylbenzamide
Selective circadian clock protein CRY1 stabilizer
Molekulargewicht: 377.51
Reinheit: 98% by HPLC NMR (Conforms)
Formulierung: White solid
CAS Nummer: [396721-89-4]
Formel: C22H23N3OS
Anwendungsbeschreibung: KL101 is an isoform-selective stabilizer of the circadian clock protein CRY1. It dose-dependently lengthened the circadian period in Bmal1-dLuc and Per2-dLuc reporter cells. KL101 strongly enhanced rosiglitazone-dependent brown adipocyte differentiation revealing the importance of CRY-dependent regulation of energy metabolism and a possible new lead for anti-obesity therapeutics.