KL101, CAS [[396721-89-4]]

Product Overview

• Article Name: KL101, CAS [[396721-89-4]]
• Biozol Catalog Number: FBM-10-3907
• Supplier Catalog Number: 10-3907
• Alternative Catalog Number: FBM-10-3907-5MG, FBM-10-3907-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: N-(2-(2,4-Dimethylphenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-yl)-3,4-dimethylbenzamide

Product Description

Selective circadian clock protein CRY1 stabilizer

Product Properties

• Molecular Weight: 377.51
• Purity: 98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [396721-89-4]
• Formula: C22H23N3OS

Application Notes

• Application Notes: KL101 is an isoform-selective stabilizer of the circadian clock protein CRY1. It dose-dependently lengthened the circadian period in Bmal1-dLuc and Per2-dLuc reporter cells. KL101 strongly enhanced rosiglitazone-dependent brown adipocyte differentiation revealing the importance of CRY-dependent regulation of energy metabolism and a possible new lead for anti-obesity therapeutics.