DRP1 inhibitor 4a

Produktübersicht

• Artikelname: DRP1 inhibitor 4a
• Artikelnummer: FBM-10-3912
• Hersteller Artikelnummer: 10-3912
• Alternativnummer: FBM-10-3912-5MG, FBM-10-3912-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: N-(4-Azetidin-1-yl)-2-phenylquinolin-6-yl)oxetane-3-carboxamide

Produktbeschreibung

Mitochondrial fission inhibitor

Produkteigenschaften

• Molekulargewicht: 359.43
• Reinheit: >98% by HPLC NMR Conforms
• Formulierung: Yellow solid
• Formel: C22H21N3O2

Anwendungsbeschreibung

• Anwendungsbeschreibung: DRP1 inhibitor 4a blocks (IC50 = 100 nM) the protein-protein interaction between dynamin related protein 1 (DRP1) and the mitochondrial membrane receptor MiD49 preventing mitochondrial fragmentation.1 It prevented roughly half of mitochondrial fragmentation in A549 cells caused by carbonylcyanide-3-chlorophenylhydrazone (CCCP).