DRP1 inhibitor 4a

Product Overview

• Article Name: DRP1 inhibitor 4a
• Biozol Catalog Number: FBM-10-3912
• Supplier Catalog Number: 10-3912
• Alternative Catalog Number: FBM-10-3912-5MG,FBM-10-3912-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

Mitochondrial fission inhibitor

Product Properties

• Molecular Weight: 359.43
• Purity: >98% by HPLC NMR Conforms
• Form: Yellow solid
• CAS Number: [Unknown]
• Formula: C22H21N3O2

Application Notes

• Application Notes: DRP1 inhibitor 4a blocks (IC50 = 100 nM) the protein-protein interaction between dynamin related protein 1 (DRP1) and the mitochondrial membrane receptor MiD49 preventing mitochondrial fragmentation.1 It prevented roughly half of mitochondrial fragmentation in A549 cells caused by carbonylcyanide-3-chlorophenylhydrazone (CCCP).