IMT1B, CAS [[2304621-06-3]]

Produktübersicht

• Artikelname: IMT1B, CAS [[2304621-06-3]]
• Artikelnummer: FBM-10-3919
• Hersteller Artikelnummer: 10-3919
• Alternativnummer: FBM-10-3919-5MG,FBM-10-3919-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: LDC203974

Produktbeschreibung

Mitochondrial DNA transcription inhibitor/RNA Polymerase inhibitor

Produkteigenschaften

• Molekulargewicht: 473.88
• Reinheit: >98% by HPLC NMR Conforms
• Formulierung: White to off-white solid
• CAS Nummer: [2304621-06-3]
• Formel: C24H21ClFNO6

Anwendungsbeschreibung

• Anwendungsbeschreibung: IMT1B (2304621-06-3) is a specific inhibitor of mitochondrial DNA (mtDNA) transcription. It targets an allosteric binding site on human mitochondrial RNA polymerase leading to impairment of biogenesis of the oxidative phosphorylation (OXPHOS) system.1 IMT1B displayed efficacy in mice containing human A2780 or DLD-1 cancer cell xenografts. IC50 = 138 nM A2780 cancer cells.2