EN450, CAS [[793719-01-4]]

Produktübersicht

• Artikelname: EN450, CAS [[793719-01-4]]
• Artikelnummer: FBM-10-3936
• Hersteller Artikelnummer: 10-3936
• Alternativnummer: FBM-10-3936-5MG,FBM-10-3936-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: N-[2-Chloro-5-(dimethylsulfamoyl)phenyl]prop-2-enamide

Produktbeschreibung

NFkB1 molecular glue

Produkteigenschaften

• Molekulargewicht: 288.75
• Reinheit: >98% by HPLC , NMR (Conforms)
• Formulierung: White to off-white solid
• CAS Nummer: [793719-01-4]
• Formel: C11H13ClN2O3S

Anwendungsbeschreibung

• Anwendungsbeschreibung: EN450 is a molecular glue that covalently interacts with a cysteine residue on the E2 ubiquitin ligase UBE2D. It displayed anti-proliferative effects in HAP1 leukemia cells. EN450s antiproliferative effects were elicited via proteasome-dependent degradation of nuclear factor kappa B subunit 1(NFkB1).1