Helicase inhibitor (S)-27, CAS [[3058652-58-4]]

Produktübersicht

• Artikelname: Helicase inhibitor (S)-27, CAS [[3058652-58-4]]
• Artikelnummer: FBM-10-3966
• Hersteller Artikelnummer: 10-3966
• Alternativnummer: FBM-10-3966-5MG, FBM-10-3966-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: (S)-1-(2-(2-Azaspiro[3.3]heptane-2-carbonyl)-4-(2-(4-(trifluoromethyl)phenyl)acetyl)piperazin-1-yl)prop-2-en-1-one. Alternate Names: Helicase inhibitor (S)-27

Produktbeschreibung

WRN helicase inhibitor

Produkteigenschaften

• Molekulargewicht: 449.47
• Reinheit: >98% by HPLC, NMR (conforms)
• Formulierung: Off-white to white solid
• CAS Nummer: [3058652-58-4]
• Formel: C23H26F3N3O3

Anwendungsbeschreibung

• Anwendungsbeschreibung: (S)-27 is a potent (pIC50(0 hr/4hr) = 5.4/7.5) inhibitor of WRN helicase. Inhibition is via covalent binding to WRN Cys727. (S)-27 inhibited (pIC50 = 5.0) the high microsatellite instability colon adenocarcinoma line SW48 (MSI-H).