Helicase inhibitor (S)-27, CAS [[3058652-58-4]]

Product Overview

• Article Name: Helicase inhibitor (S)-27, CAS [[3058652-58-4]]
• Biozol Catalog Number: FBM-10-3966
• Supplier Catalog Number: 10-3966
• Alternative Catalog Number: FBM-10-3966-5MG,FBM-10-3966-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Helicase inhibitor (S)-27

Product Description

WRN helicase inhibitor

Product Properties

• Molecular Weight: 449.47
• Purity: >98% by HPLC, NMR (conforms)
• Form: Off-white to white solid
• CAS Number: [3058652-58-4]
• Formula: C23H26F3N3O3

Application Notes

• Application Notes: (S)-27 is a potent (pIC50(0 hr/4hr) = 5.4/7.5) inhibitor of WRN helicase. Inhibition is via covalent binding to WRN Cys727. (S)-27 inhibited (pIC50 = 5.0) the high microsatellite instability colon adenocarcinoma line SW48 (MSI-H).