Pridopidine, CAS [[346688-38-8]]

Produktübersicht

• Artikelname: Pridopidine, CAS [[346688-38-8]]
• Artikelnummer: FBM-10-4003
• Hersteller Artikelnummer: 10-4003
• Alternativnummer: FBM-10-4003-5MG, FBM-10-4003-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 4-(3-(Methylsulfonyl)phenyl)-1-propylpiperidine. Alternate Names: ACR16

Produktbeschreibung

Sigma-1 ligand/neuroprotective/restorative

Produkteigenschaften

• Molekulargewicht: 281.41
• Reinheit: 98% by TLC NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [346688-38-8]
• Formel: C15H23NO2S

Anwendungsbeschreibung

• Anwendungsbeschreibung: Pridopidine is being studied as a potential treatment for Huntingtons disease, Parkinsons disease, and schizophrenia based on its locomotor stabilizing and antipsychotic-like effects.1,2 It was, unusually, able to reverse both hypo- and hyperdopaminergia depending on local dopamine concentrations without inducing catalepsy. This was originally attributed to functional dopamine D2 antagonism with fast on/off kinetics (''dopamine stabilizer).3 More recent studies have attributed pridopidines effects to its being a more potent sigma-1 ligand than a D2 ligand.4,5 Displays neuroprotective/restorative effects6,7 and ameliorates central features of amyotrophic lateral sclerosis pathology8 in a sigma-1-mediated manner