MPEP HCl, CAS [[219911-35-0]]

Produktübersicht

• Artikelname: MPEP HCl, CAS [[219911-35-0]]
• Artikelnummer: FBM-10-4007
• Hersteller Artikelnummer: 10-4007
• Alternativnummer: FBM-10-4007-5MG, FBM-10-4007-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 2-Methyl-6-(2-phenylethynyl)pyridine hydrochloride

Produktbeschreibung

mGlu5 receptor antagonist

Produkteigenschaften

• Molekulargewicht: 229.71
• Reinheit: 98% by HPLC, NMR (Conforms)
• Formulierung: White or pale yellow solid
• CAS Nummer: [219911-35-0]
• Formel: C14H11NHCl

Anwendungsbeschreibung

• Anwendungsbeschreibung: MPEP is a potent (IC50 = 36 nM for quisqualate-stimulated phosphoinositide hydrolysis) and selective (over mGlu1b, -2, -3, -4a, -6, -7b, and -8a) antagonist of the metabotropic glutamate receptor subtype 5 (mGlu5).1 It is a positive allosteric modulator of human mGlu4.2 MPEP inhibition of mGlu5 has been studied for the treatment of many CNS disorders including Parkinsons3,4, Fragile X syndrome5, and addiction6.